As of Oct 12, 2020, the average annual pay for a Nurse Anesthetist in San Diego, CA is $175,114 a year. The average salary for a Nurse Anesthetist (CRNA) with Anesthesia skills in San Diego, California is $172,464. US Navy Certified Registered Nurse Anesthetist salaries - 2 salaries reported: San Diego, CA Area: $176,812 / yrKaiser Permanente Certified Registered Nurse Anesthetist salaries - 1 salaries reported: San Diego, CA Area: $118 / hr In addition, they earn an average bonus of $6,471. While ZipRecruiter is seeing annual salaries as high as $211,048 and as low as $98,625, the majority of Nurse Anesthetist salaries currently range between $162,501 (25th percentile) to $196,739 (75th percentile) in San Diego, CA. The average chief nurse anesthetist salary in San Diego, California is $211,774 or an equivalent hourly rate of $102. The average registered nurse anesthetist salary in San Diego, California is $193,748 or an equivalent hourly rate of $93. This is 10% higher (+$17,510) than the average registered nurse anesthetist salary in the United States. This is 11% higher (+$21,038) than the average chief nurse anesthetist salary in the United States. In addition, they earn an average bonus of $7,730.