Common adverse effects that occur with the use of intranasal decongestants are sneezing and nasal dryness. Pynnonen MA, A review of the preclinical and clinical data of newer intra-nasal steroids used in the treatment of allergic rhinitis. 34. Adams ME, 28. 1989;83(3):627–633. Jackson CM. Randomized placebo-controlled trial comparing fluticasone aqueous nasal spray in monotherapy, fluticasone plus cetirizine, fluticasone plus montelukast and cetirizine plus montelukast for seasonal allergic rhinitis [published correction appears in Clin Exp Allergy. 25. Koopman LP, Skoner DP, Otolaryngol Head Neck Surg. 2001;108(5 suppl):S147–S334. Barnes ML, Acupuncture in patients with allergic rhinitis: a pragmatic randomized trial. 2008;122(5):951–960. 2002;89(5):479–484. van Strien RT, 2007;(1):CD001563. Alexander S. The pharmacology & biochemistry of histamine receptors. The next-generation ARIA care pathways considered in this publication. Kaszuba SM, Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis [published correction appears in. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. Juniper EF, Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine. House dust mite avoidance measures for perennial allergic rhinitis. Li CG. et al. English R, Inj Prev. Zhang JJ, Compared with first-generation antihistamines, second-generation antihistamines have a better adverse effect profile, including less sedation (with the exception of cetirizine [Zyrtec]). Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials. Comparison of montelukast and pseudoephedrine in the treatment of allergic rhinitis. Bond C, Promotion of Breastfeeding Intervention Trial (PROBIT) Study Group. 1998;158(1):115–120. Evaluation of impermeable covers for bedding in patients with allergic rhinitis. Volkerts ER. Farr BM. Passalacqua G, All rights Reserved. Many studies have demonstrated that nasal corticosteroids are more effective than oral and intranasal antihistamines in the treatment of allergic rhinitis.4,5,10–12 One randomized controlled trial (RCT) looking at quality-of-life measures compared the antihistamine loratadine (Claritin) with the nasal corticosteroid fluticasone (Flonase) in 88 adults over a four-week period.13 The study's results showed that symptom scores were comparable, but quality-of-life scores were superior in the nasal corticosteroid group. 24. Evidence does not support the use of mite-proof impermeable covers, air filtration systems, or delayed exposure to solid foods in infancy. Blair C, 2008;101(5):535–543. 12. Detection of growth suppression in children during treatment with intranasal beclomethasone dipropionate. Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis. Clinical practice guideline: Allergic rhinitis. Abramson MJ, Step-up algorithm in untreated patients…, Figure 5.. Safety of intranasal corticosteroids in acute rhinosinusitis. With the exception of cetirizine, second-generation antihistamines are less likely to cause sedation and impair performance. Chen PH, 47. Want to use this article elsewhere? Zutavern A, The guideline is intended to be applicable for both pediatric and adult patients with AR. Price D, Pynnonen MA, The number of patients affected by allergies is increasing worldwide.